Fig. 4: Therapeutic effects of PRFE in two treatment modes on full-thickness skin wounds in animal models.
From: Smartphone administered pulsed radio frequency energy therapy for expedited cutaneous wound healing
a Illustration for development of the full-thickness circular shaped skin wound (top) and linear incisional wound (bottom). b Schematic diagram of the test setup and PRFE treatment on a rat. c Wound healing process of PRFE-Bandage treatment group and the corresponding control group (top PRFE-C and bottom for PRFE-L) under treatment Mode 1. d Wound healing process of PRFE-Bandage treatment group and the corresponding control group (top PRFE-C and bottom for PRFE-L) under treatment Mode 2. e Relative wound size (with mean and variance) during the healing process for both circular and linear wounds (left), circular (middle) and linear (right) wounds under two modes. (For two-tailed paired t-test, **** indicates P < 0.0001, *** indicates P < 0.001, ** indicates P < 0.01, * indicates P < 0.05, and. indicates P < 0.1). f The average wound closure variations of all groups under two modes.
