Table 3 Detection rate of adverse maternal and neonatal outcomes of the baseline, MAP and PROMPT model

From: Noninvasive early prediction of preeclampsia in pregnancy using retinal vascular features

Screening model/ FPR for PE

PE n = 86

PT PE n = 29

AO n = 393

Severe AO n = 98

Ā 

DR%

PPV%

DR%

DR%

PPV%

DR%

PPV%

Baseline model

5%

27.9 (19.5, 38.2)

21.2 (14.2, 29.7)

31.0 (17.3, 49.2)

9.7 (7.1, 13.0)

33.6 (25.6, 42.7)

13.3 (7.9, 21.4)

11.5 (6.8, 18.7)

10%

39.5 (29.9, 50.1)

16.6 (12.1, 22.3)

44.8 (28.4, 62.5)

16.5 (13.2, 20.5)

31.7 (25.7, 38.4)

21.4 (14.5, 30.5)

10.2 (6.8, 15.2)

15%

52.3 (41.9, 62.6)

15.0 (11.4, 19.4)

69.0 (50.8, 82.7)

23.9 (20.0, 28.4)

31.2 (26.3, 36.7)

34.7 (26.0, 44.5)

11.3 (8.2, 15.4)

MAP model

5%

41.9 (32, 52.4)

29.5 (22.1, 38.1)

55.2 (37.5, 71.6)

13.5 (10.5, 17.2)

43.4 (35, 52.3)

22.4 (15.3, 31.7)

18.0 (12.2, 25.8)

10%

59.3 (48.7, 69.1)

22.9 (17.8, 28.8)

69.0 (50.8, 82.7)

22.4 (18.5, 26.8)

39.5 (33.3, 46)

31.6 (23.3, 41.4)

13.9 (10, 19.1)

15%

64 (53.4, 73.3)

17.7 (13.8, 22.3)

72.4 (54.3, 85.3)

28.2 (24, 32.9)

35.7 (30.6, 41.2)

37.8 (28.8, 47.6)

11.9 (8.8, 16)

PROMPT model

5%

47.7 (37.4, 58.1)

32.3 (24.8, 40.8)

62.1 (44, 77.3)

16.8 (13.4, 20.8)

52 (43.3, 60.5)

27.6 (19.7, 37.1)

21.3 (15, 29.2)

10%

60.5 (49.9, 70.1)

23.1 (18.1, 29)

79.3 (61.6, 90.2)

23.4 (19.5, 27.8)

40.9 (34.7, 47.4)

35.7 (26.9, 45.6)

15.6 (11.4, 20.9)

15%

72.1 (61.8, 80.5)

19.3 (15.4, 24)

82.8 (65.5, 92.4)

31.0 (26.7, 35.8)

38.0 (32.9, 43.4)

40.8 (31.6, 50.7)

12.5 (9.3, 16.5)

  1. Values in parentheses are 95% CI. AO was defined as any one or more of the following maternal and neonatal outcomes: PE, SGA (birth weight < 10th percentile), and PTB ( < 37 weeks). Severe AO was defined as any one or more of the following maternal and neonatal outcomes: PT PE, severe SGA (birth weight < 3rd percentile), and early PTB ( < 34 weeks).
  2. FPR false positive rate, PE preeclampsia, PT-PE preterm preeclampsia, AO adverse pregnancy outcomes, DR detection rate, PPV positive predictive value, MAP Mean arterial pressure, PROMPT Preeclampsia Risk factors + Ophthalmic data + Mean arterial pressure Prediction Test.