Table 1 Opioid mentions, unique opioid comments, and unique users mentioning opioids on Reddit between January 2006 and December 2022

From: Monitoring the opioid epidemic via social media discussions

Drug

Opioid Class

Mentions

Comments

Users

Heroin

Heroin

2,087,560

2,048,960

1,473,202

Morphine

Full Agonist

457,885

435,300

328,491

Fentanyl

Full Agonist

393,993

370,313

262,710

Oxycodone

Full Agonist

359,244

363,869

260,609

Naloxone

Antagonist

362,160

345,618

203,306

Hydrocodone

Full Agonist

306,704

302,852

224,750

Methadone

Full Agonist

282,839

268,525

154,799

Codeine

Full Agonist

216,807

210,109

152,371

Tramadol

Full Agonist

157,086

144,402

96,556

Hydromorphone

Full Agonist

101,425

99,344

70,813

Buprenorphine

Partial Agonist

97,798

92,856

58,277

Loperamide

Partial Agonist

84,013

82,936

61,082

Naltrexone

Antagonist

72,317

70,679

43,845

Pethidine

Full Agonist

13,884

13,328

10,599

Nalmefene

Antagonist

1074

5278

3659

Nalbuphine

Mixed Agonist

1942

1834

1383

Sufentanil

Full Agonist

1812

1771

1395

Butorphanol

Mixed Agonist

1585

1535

1201

Pentazocine

Mixed Agonist

1075

1018

823

Levorphanol

Full Agonist

478

439

340

Diprenorphine

Antagonist

526

337

262

Nalorphine

Mixed Agonist

55

51

43

Dezocine

Mixed Agonist

47

36

26

  1. Heroin has more than four times the number of comments of the next most talked about opioid (Morphine) and is mentioned by the broadest number of users. The number of mentions quickly decreases for lesser-known opioids, especially those of the mixed agonist class (e.g., Nalbuphine).