Table 4 Sample Knowledge Entry from the RAG Knowledge Base
From: Retrieval-augmented generation elevates local LLM quality in radiology contrast media consultation
Topic | Question-Answer Format |
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Precautions for Contrast Media Administration in Patients with Renal Dysfunction | Q: What are the important precautions and considerations when administering contrast media to patients with renal dysfunction? A: • Pre-existing renal dysfunction is considered a risk factor for acute renal failure caused by iodinated contrast media, with eGFR now commonly used as the preferred indicator of renal function - Patients with eGFR below 30 mL/min/1.73 m² face significantly increased risk and require sufficient preventive measures - Contrast-induced nephropathy (CIN) is defined as an increase in serum creatinine level by 0.5 mg/dL or 25% or more from baseline within 72 hours after contrast media administration - Key risk factors for CIN include advanced age, diabetes with chronic kidney disease (CKD), use of diuretics (especially loop diuretics), and use of NSAIDs - Appropriate hydration protocols using normal saline solution or sodium bicarbonate solution are recommended as preventive measures - Repeated contrast-enhanced CT scans within a short period (24-48 hours) should be avoided |