Table 4 Sample Knowledge Entry from the RAG Knowledge Base

From: Retrieval-augmented generation elevates local LLM quality in radiology contrast media consultation

Topic

Question-Answer Format

Precautions for Contrast Media Administration in Patients with Renal Dysfunction

Q: What are the important precautions and considerations when administering contrast media to patients with renal dysfunction?

A: • Pre-existing renal dysfunction is considered a risk factor for acute renal failure caused by iodinated contrast media, with eGFR now commonly used as the preferred indicator of renal function

- Patients with eGFR below 30 mL/min/1.73 m² face significantly increased risk and require sufficient preventive measures

- Contrast-induced nephropathy (CIN) is defined as an increase in serum creatinine level by 0.5 mg/dL or 25% or more from baseline within 72 hours after contrast media administration

- Key risk factors for CIN include advanced age, diabetes with chronic kidney disease (CKD), use of diuretics (especially loop diuretics), and use of NSAIDs

- Appropriate hydration protocols using normal saline solution or sodium bicarbonate solution are recommended as preventive measures

- Repeated contrast-enhanced CT scans within a short period (24-48 hours) should be avoided

  1. Example of a structured entry used in the retrieval-augmented generation (RAG) system, formatted as a clinical question and answer. This entry addresses precautions for administering contrast media to patients with renal dysfunction.