Table 1 Comparison of retinal microvascular features among the high, middle, and low-risk groups

From: Phenotypic screening and genetic insights for predicting major vascular-related diseases using retinal imaging

  

Overall

Low-risk

Middle-risk

High-risk

p

Characteristic

Number

25,840

5505

18,637

1698

 

Binary

Fractal dimension (−)

1.489 (0.035)

1.502 (0.032)

1.487 (0.034)

1.464 (0.035)

<2.22E−16

Vessel density (−)

0.071 (0.010)

0.074 (0.010)

0.070 (0.010)

0.064 (0.010)

<2.22E−16

Average width (pixel)

7416.400 (617.994)

7389.829 (622.269)

7417.583 (616.561)

7519.605 (607.894)

3.19E−09

Distance tortuosity (−)

3.397 (1.189)

3.245 (1.066)

3.426 (1.206)

3.674 (1.385)

<2.22E−16

Squared curvature tortuosity (−)

23.996 (23.416)

21.373 (20.112)

24.569 (24.138)

27.818 (25.869)

<2.22E−16

Tortuosity density (−)

0.699 (0.034)

0.696 (0.033)

0.700 (0.034)

0.706 (0.037)

<2.22E−16

Artery

Fractal dimension (−)

1.292 (0.037)

1.305 (0.034)

1.290 (0.036)

1.266 (0.040)

<2.22E−16

Vessel density (−)

0.030 (0.005)

0.032 (0.005)

0.030 (0.005)

0.027 (0.005)

<2.22E−16

Average width (pixel)

7284.574 (672.663)

7333.591 (661.714)

7263.419 (674.145)

7358.619 (684.664)

2.11E−12

Distance tortuosity (−)

5.568 (3.512)

5.202 (3.014)

5.655 (3.609)

6.009 (4.058)

<2.22E−16

Squared curvature tortuosity (−)

72.730 (114.306)

61.280 (88.177)

75.250 (119.975)

89.182 (132.148)

<2.22E−16

Tortuosity density (−)

0.750 (0.054)

0.747 (0.053)

0.751 (0.054)

0.754 (0.059)

7.96E−06

Vein

Fractal dimension (−)

1.315 (0.039)

1.327 (0.037)

1.313 (0.039)

1.293 (0.039)

<2.22E−16

Vessel density (−)

0.036 (0.006)

0.037 (0.006)

0.035 (0.006)

0.033 (0.005)

<2.22E−16

Average width (pixel)

8009.407 (790.017)

7887.956 (746.560)

8024.175 (793.901)

8350.661 (808.945)

<2.22E−16

Distance tortuosity (−)

3.491 (1.835)

3.344 (1.637)

3.518 (1.867)

3.788 (2.153)

2.62E−14

Squared curvature tortuosity (−)

27.271 (39.951)

25.069 (37.253)

27.730 (40.530)

30.795 (43.015)

3.49E−06

Tortuosity density (−)

0.760 (0.042)

0.757 (0.040)

0.761 (0.042)

0.764 (0.047)

1.31E−08

 

Age Gap (year)

−0.593 (5.226)

−3.735 (4.531)

−0.138 (4.938)

4.597 (4.502)

<2.22E−16

  1. # − indicates that this indicator is a unitless measure.