Table 2 Demographic and radiologic factors of unicompartmental versus tricompartmental OA

From: Osteoarthritis progression pattern based on patient specific characteristics using machine learning

Variable

Unicompartmental OA (n = 479)

Tricompartmental OA (n = 354)

P-value

Initial visit

Final visit

Unicompartmental OA

Tricompartmental OA

P-value

Unicompart- mental OA

Tricompartmental OA

P-value

Demographic factors

OARSI grade for radiographic factors

Age (years, initial visit)

56.0 ± 9.9

60.5 ± 7.9

<0.001

 JSN (mean grade)

Age (years, final visit)

66.9 ± 9.7

71.4 ± 7.6

<0.001

 MTF

0.7 ± 0.5

0.6 ± 0.5

0.011

1.3 ± 0.6

2.0 ± 0.9

<0.001

Sex (male/female)

95/384

72/282

NS

 LTF

0.0 ± 0.1

0.1 ± 0.3

0.021

0.0 ± 0.2

0.3 ± 0.7

<0.001

BMI (kg/m2)

24.0 ± 2.8

25.7 ± 3.3

<0.001

 PF

0.0 ± 0.2

0.2 ± 0.4

<0.001

0.2 ± 0.4

1.3 ± 0.7

<0.001

BMD (lowest T-score)

−1.2 ± 1.3

−2.0 ± 1.1

<0.001

 Osteophyte (mean grade)

Metabolic disease

243 (50.7%)

266 (75.1%)

<0.001

 MF

0.3 ± 0.5

0.9 ± 0.7

<0.001

1.3 ± 0.8

2.4 ± 0.7

<0.001

 HTN

245 (51.4%)

212 (59.9%)

0.012

 LF

0.1 ± 0.3

0.4 ± 0.5

<0.001

0.2 ± 0.5

1.9 ± 0.7

<0.001

 DM

83 (17.3%)

127 (35.9%)

<0.001

 MT

0.4 ± 0.5

0.7 ± 0.6

<0.001

1.0 ± 0.7

1.8 ± 0.6

<0.001

Dyslipidemia

160 (33.4%)

172 (48.6%)

<0.001

 LT

0.1 ± 0.3

0.3 ± 0.5

<0.001

0.2 ± 0.4

1.7 ± 0.8

<0.001

Other comorbidities

114 (23.8%)

102 (28.8%)

NS

 PF

0.1 ± 0.3

0.5 ± 0.5

<0.001

0.2 ± 0.4

1.8 ± 0.6

<0.001

Follow-up period (months)

10.9 ± 2.9

10.9 ± 3.7

NS

       
  1. OA, osteoarthritis, NS not significant, BMI body mass index, BMD bone mineral density, HTN hypertension, DM diabetes mellitus, OARSI Osteoarthritis Research Society International, JSN joint space narrowing, MTF medial tibiofemoral, LTF lateral tibiofemoral, PF patellofemoral, MF medial femoral condyle, LF lateral femoral condyle, MT medial tibial plateau, LT lateral tibial plateau.