Extended Data Fig. 2: Detailed analysis of electrographic seizure dynamics for the representative sham and tFUS cases. | Nature Electronics

Extended Data Fig. 2: Detailed analysis of electrographic seizure dynamics for the representative sham and tFUS cases.

From: A shape-morphing cortex-adhesive sensor for closed-loop transcranial ultrasound neurostimulation

Extended Data Fig. 2

a, b, Timetrace of neural activity recorded from a single channel (Ch.9) for the full sequence of the sham seizure episode (a), and that of the tFUS seizure suppression episode (b). c, d, Two-dimensional amplitude topographic frames of electrographic seizures illustrating the spatiotemporal pattern occurring within the duration of interest from the sham (c), and tFUS (d) cases. The seizure-related events of the selected duration include seizure spike wave (SW) initiation (*1 in phase I), continuous SW (*2 in phase II), and seizure SW termination (transition to interictal phase for sham case and seizure suppression for tFUS case) (*3 in phase III).

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