Extended Data Fig. 1: Length dependency of albicidin-mediated DNA cleavage.
From: Molecular mechanism of topoisomerase poisoning by the peptide antibiotic albicidin
Position of cleaved DNA indicated by arrows and red dots. ATP and ADPNP were added as indicated, (----) stands for no nucleotide added. 20 nM gyrase, 1 µM albicidin and 25 nM DNA was used in each reaction.
