Fig. 3: Reactivity evaluation of anti-Markovnikov hydrochlorination. | Nature Catalysis

Fig. 3: Reactivity evaluation of anti-Markovnikov hydrochlorination.

From: Anti-Markovnikov hydrochlorination and hydronitrooxylation of α-olefins via visible-light photocatalysis

Fig. 3

Reaction conditions: alkene (0.3 mmol), HCl(aq. 37%) (0.45 mmol), 1 (10 mol%), bis(4-methoxyphenyl) disulfide (10 mol%) in fluorobenzene/acetone (3 ml, 5:1 v/v) at 33 °C under 2 × 40 W blue light-emitting diodes (LEDs) for 24 h. i and ii denote the site of Cl of the major/minor products. See Supplementary Methods for the detailed experimental procedure. aReaction performed with 4-chloropyridine hydrochloride (0.45 mmol). bReaction performed on a 1.2 mmol scale, 48 h. cDiastereomeric ratio = 1:1.

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