The 2025 RepArtZymes conference featured the latest developments in the design and development of artificial and repurposed enzymes for synthetic and biotechnological applications. These contributions illustrate the impact of this rapidly expanding research area towards addressing key challenges in organic synthesis, medicinal chemistry, polymer chemistry, energy conversion, and environmental remediation.
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References
Schwizer, F. et al. Chem. Rev. 118, 142–231 (2018).
Birch-Price, Z., Hardy, F. J., Lister, T. M., Kohn, A. R. & Green, A. P. Chem. Rev. 124, 8740–8786 (2024).
Brandenberg, O. F., Fasan, R. & Arnold, F. H. Curr. Opin. Biotechnol. 47, 102–111 (2017).
Kennemur, J. L., Long, Y., Co, C. J., Das, A. & Arnold, F. H. J. Am. Chem. Soc. 147, 27165–27171 (2025).
Roy, S. et al. Nat. Catal. 7, 65–76 (2024).
Huang, J. et al. Nature 617, 403–408 (2023).
Zhang, X. et al. Nature 644, 381–390 (2025).
Mu, X. et al. Nat. Catal. 8, 635–644 (2025).
Xing, Z. et al. Nature 637, 1118–1123 (2025).
Lu, Y.-C. et al. J. Am. Chem. Soc. 147, 17804–17816 (2025).
Raps, F. C., Rivas-Souchet, A., Jones, C. M. & Hyster, T. K. Nature 637, 362–368 (2025).
Tseliou, V. et al. Nature 634, 848–854 (2024).
Bahukhandi, S. B. et al. Angew. Chem. Int. Ed. https://doi.org/10.1002/anie.202505431 (2025).
Trimble, J. S. et al. Nature 611, 709–714 (2022).
Sun, N. et al. Nature 611, 715–720 (2022).
Veen, M. J. et al. Angew. Chem. Int. Ed. 64, e202421912 (2025).
Abramson, J. et al. Nature 630, 493–500 (2024).
Jeong, W. J., Ha, S. & Song, W. J. Chem https://doi.org/10.1016/j.chempr.2025.102644 (2025).
Vargas, D. A. et al. Nat. Chem. 16, 817–826 (2024).
Ariyasu, S. et al. ACS Catal. 13, 8613–8623 (2023).
Cribari, M. A. et al. J. Am. Chem. Soc. 145, 27380–27389 (2023).
Ospina, F. et al. Angew. Chem. Int. Ed. https://doi.org/10.1002/anie.202510300 (2025).
Zetzsche, L. E. et al. Nature 603, 79–85 (2022).
Zeng, Q.-Q. et al. Nat. Synth. 3, 1340–1348 (2024).
Wang, H. et al. Nat. Chem. 17, 74–82 (2025).
Labidi, R. J. et al. J. Am. Chem. Soc. 146, 28296–28305 (2024).
Van Stappen, C. et al. J. Am. Chem. Soc. 145, 20610–20623 (2023).
Belluati, A. et al. Nat. Chem. 16, 564–574 (2024).
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Fasan, R. Pushing the boundaries of biocatalysis. Nat Catal 8, 867–869 (2025). https://doi.org/10.1038/s41929-025-01415-5
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DOI: https://doi.org/10.1038/s41929-025-01415-5
