Table 3 Affinity parameter of the interaction between OMD, muteins, and collagen
From: Molecular basis for governing the morphology of type-I collagen fibrils by Osteomodulin
|  | KD (µM) | Binding (RU) |
|---|---|---|
OMD | 24.6 | 37.2 |
E284R/E303R | n.d. | −0.5 |
chOMD | 25.4 | 117.8 |
chE173R | 51.4 | 118.3 |
chE225R | 29.1 | 105.6 |
chD254R | 22.3 | 74.8 |
chD271R | 25.6 | 71 |
chN278R | 14.3 | 47.4 |
chE284R | 32000 | 22.3 |
chE303R | 72.4 | 3.7 |
chE311R | 5.48 | 22.6 |
chE284R/E303R | n.d. | −5.5 |
chE284A | 78.3 | 57.4 |
chE303A | n.d. | −0.5 |
