Fig. 6 | Communications Biology

Fig. 6

From: Acquisition of resistance to carbapenem and macrolide-mediated quorum sensing inhibition by Pseudomonas aeruginosa via ICETn43716385

Fig. 6

Heatmap of 550 genes that are differentially expressed between the azithromycin (AZM)-treated and non-treated PAO1, and their behaviors in the AZM-treated and non-treated PAO1/pUCP18::msr(E). The differentially expressed genes (fold change >4, P value < 0.05) between the AZM-treated and non-treated PAO1 cells were identified by performing a negative binomial test using the DESeq 2 package of R/Bioconductor (n = 3). Such changes in the gene expression profiles were not observed between PAO1/pUCP18::msr(E)-treated and non-treated with AZM. The complete lists of differentially expressed genes between AZM-treated and non-treated PAO1 and between AZM-treated and non-treated PAO1/pUCP18::msr(E) can be found in Supplementary Data 3 and 4

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