Fig. 3
p66Shc and CD36 expressions are increased in plaque-associated macrophages in diabetic patients. Representative co-immunofluorescence images for p66Shc (red, a, left panel), CD36 (red, b, left panel), MOMA-2 (green, a, b, left panels), and DAPI nuclear counterstain (blue) and dot plot summarising data (Icorr; correlation index, right panels). Co-localization of p66Shc and CD36 with the macrophage marker MOMA-2 is increased in diabetic patient’s samples (N = 10) as compared to non-diabetic patient’s samples (N = 10). DM: diabetic patient’s samples; non-DM: non-diabetic patient’s samples. Data shown as dot plots represent mean ± SEM of 10 patients per group, size bars: 20 µm; **P < 0.01; a Mann–Whitney U test, b t-test
