Table 1 Data-collection and final refinement statistics

 Space group

P2₁2₁2₁

P6₅22

  a, b, c (Å)

65.65, 112.28, 318.54

81.08, 81.08, 162.94

  α, β, γ (°)

90.0, 90.0, 90.0

90.0, 90.0, 120.0

 Resolution (Å)

47.99–2.90 (3.06–2.90)^a

53.19–2.75 (2.85–2.75)^a

 R _merge

0.06 (0.42)^a

0.07 (0.33)^a

 〈I/σ(I)〉

16.7 (3.3)^a

11.7 (5.0)^a

 Completeness (%)

99.9 (100)^a

99.8 (100)^a

 Redundancy

3.7 (3.9)^a

5.6 (6.1)^a

 Resolution (Å)

53.19–2.75

 No. of reflections

8742

 R_work/R_free 

0.241/0.292

 Completeness (%)

99.58

 No. of non-hydrogen atoms

1855

      Protein

1828

  Ligands

12

  Water

15

  Protein

67.31

  Ligands

78.36

  Water

45.16

  Bond lengths (Å)

0.012

  Bond angles (°)

1.47