Fig. 1
From: Large conformational changes of a highly dynamic pre-protein binding domain in SecA
The position of the pre-protein binding domain (PBD) is not a common denominator in known SecA structures. Atomic model of SecA proteins from B. subtilis in the (a) so-called wide open conformation (1M74) and (b) in the open conformation (1TF2), respectively. The two SecA crystal structures depicted here were both obtained in the presence of adenosine diphosphate (ADP) and differ largely by the position of the PBD (yellow). The ADP binding cleft is coloured in pink. The double-headed arrow highlights the proposed mobility of the PBD
