Fig. 4 | Communications Biology

Fig. 4

From: 2D polarization imaging as a low-cost fluorescence method to detect α-synuclein aggregation ex vivo in models of Parkinson’s disease

Fig. 4

Accessory olfactory bulbs images at low and high magnification. The figure presents two old (a, b) and two young (c, d) mice showing high expression of α-synuclein-GFP. Higher magnification images are presented on the right column of each panel. In some areas of the old mice anti-correlation between fluorescence intensity and ε is clearly visible while this is absent in the same areas of the young mice AOB. Contours lines are added in the higher magnification images to guide the eye so the correlation between fluorescence intensity and energy funneling efficiency is clearer. Contour lines are calculated using the ε image, where all values inside the contour line are larger (or smaller) than an arbitrarily chosen threshold. Scale bars are 200 and 20 μm long for the low and high magnification images, respectively

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