Fig. 2
From: i-BLESS is an ultra-sensitive method for detection of DNA double-strand breaks

Comparison of i-BLESS and Break-seq. a Design of Break-seq renders it unable to detect blunt ends and 3′-overhangs. P and D correspond to proximal and distal adapters, respectively. b i-BLESS and Break-seq signals around early replication origins (dotted vertical lines) in a representative region of chromosome XV for HU treated mec1-1 sml1-1 cells. Reads were normalized to 1 million total reads