Fig. 1 | Communications Biology

Fig. 1

From: Structure-function-guided exploration of the antimicrobial peptide polybia-CP identifies activity determinants and generates synthetic therapeutic candidates

Fig. 1

Schematic of the structure-function-guided exploration approach leveraged to generate peptide antibiotics. a The wasp venom derived antimicrobial peptide Polybia-CP was subjected to structure-function analysis to elucidate determinants responsible for biological activity. b Data from antimicrobial activity, physicochemical properties, and structure analyses was harnessed to c identify functional determinants and generate enhanced synthetic variants with therapeutic potential

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