Fig. 1 | Communications Biology

Fig. 1

From: Global analysis of tRNA and translation factor expression reveals a dynamic landscape of translational regulation in human cancers

Fig. 1

Overview of tRNA expression across multiple cancer types. a Distribution of tRNA expression value (Y-axis, log2 TMM) across 31 cancer types (X-axis). Please refer Supplementary Figure 1D and Supplementary Table 1 for full cancer names. For each violin plot, the center dot represents median; the bold line represents 1.5× interquartile range. b Clustering of tRNA expression across cancer types. Nodes A, B, and C, respectively, denote the high-, middle-, and low-expression groups. X-axis represents 31 cancer types and Y-axis represents the expression value of tRNA genes (log2(TMM)). The right colored bar stands for 22 tRNAamino acids. c Percentage of tRNAs in different groups based on their expression group in b. Different tRNA genes for the same amino acid or function (i.e., Met divide into iMet and Met base on their divergent function) are grouped together

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