Fig. 2 | Communications Biology

Fig. 2

From: Global analysis of tRNA and translation factor expression reveals a dynamic landscape of translational regulation in human cancers

Fig. 2

Differential expression of tRNA genes across different cancer types. a tRNAs differentially expressed in at least eight cancer types. Red denotes up-regulation; blue denotes down-regulation (|fold-change| ≥ 1.5, FDR < 0.05). X-axis represents 15 cancer types with > 5 tumor-normal paired miRNA-seq samples. The color bar denotes to tRNAs based on their decoded amino acids or function. b Percentage of differentially expressed tRNAs among amino acid groups. Each dot denotes a cancer type. The boxes show the median ± 1 quartile, with whiskers extending to the most extreme data point within 1.5 interquartile range from the box boundaries. c Percentage of up-regulated (red bars) and down-regulated (blue bars) tRNAs across different cancer types. X-axis represents 15 cancer types with > 5 tumor-normal paired miRNA-seq samples

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