Table 1 Periods of oscillation of [cAMP]i and cell velocity at three developmental stages

From: Collective cell migration of Dictyostelium without cAMP oscillations at multicellular stages

 

Early aggregation

Loose mound

Tight mound

Slug

Periods of cell velocity (min)

5.58 ± 0.47

2.48 ± 0.22

4.78 ± 0.31

5.32 ± 1.09

Periods of [cAMP]i oscillation (min)

5.62 ± 0.36

2.47 ± 0.28

4.70 ± 0.56

ND

Phase difference between cell velocity and [cAMP]i oscillation (min)

0.29 ± 0.29

1.26 ± 0.26

0.15 ± 0.12

ND

  1. Mean values ± SD are shown. Sample numbers are as follows: 100 cells in 6 aggregation centers (early aggregation), 45 cells in 7 mounds (loose mound stage), 47 cells in 5 mounds (tight mound stage), and 20 cells in 11 slugs (slug stage). The periods of [cAMP]i oscillations and cell velocities in the loose mound stage are significantly shorter than those in the early aggregation and the tight mound stages (P< 10–5: Student’s two-tailed t-test)
  2. ND no detection of periodicity