Table 4 Summary of results showing the functional performance of the pathogenic mutant Pf-R in comparison with nonpathogenic counterparts46
From: Bridging human chaperonopathies and microbial chaperonins
Gene | E. coli exp. | Mixed oligomers | Hexadecamers | ||||||
|---|---|---|---|---|---|---|---|---|---|
Heat res. | ATPase | Disperse fibrils | Form hexadecamers | Protection | |||||
MDH | MDH | SAP | |||||||
37 °C | 42 °C | 37 °C | 50 °C | ||||||
Pf-CD1 | 100 | 100 | 100 | 100 | 100 | 100 | 100 | 100 | 100 |
Pf-H | 100 | 100 | 100 or less | 100 or less | 100 or less | 100 | 100 | 100 | 100 |
Pf-R | 100 | 100 | Low | Low | Low | Low | Low | 100 | 100 |
