Fig. 2
The coupling effect between the PEP binding affinity and an allosteric effector by the linked-function analysis. The profile of Ka values for PEP of PKM2 (wild-type, H391Y, or R399E) vs. an effector (FBP, Ser, or Phe) was measured. Data from three independent experiments are presented as mean ± SD. WT, wild-type
