Fig. 4
From: Human cortical folding across regions within individual brains follows universal scaling law

Slope and offset over age for Alzheimer’s subjects. a Slope estimates based on different lobes of the same hemisphere (box plots) for Alzheimer’s patients (AD) and controls. As a reference the horizontal grey line indicates the predicted 1.25 slope. To enable comparison, we also show the group-based slope estimates as grey error bars. b Offset (assuming 1.25 as slope) is shown for AD and control groups for different lobes. Solid line indicates the mean, and shaded area shows the 95% bootstrapped confidence intervals for the mean. c Effect size of offset (KLobe) from the control vs. AD between-group comparisons at different lobes. Empty circles show where the effect was significant (p < 0.05) under a two-sided ranksum test