Fig. 3

fRPE-selective genes are enriched in monogenic and polygenic diseases. a Genes causal for inherited retinal disorders (IRD) have elevated expression in fRPE. b, c Variants near RPE-selective genes explain a larger proportion of AMD (b) and myopia (c) risk than those near GTEx tissue-selective genes. The red bar represents the top 500 fRPE-selective genes