Fig. 3
From: Extracellular vesicle microRNA quantification from plasma using an integrated microfluidic device
Representative CVCs for the integrated microfluidic platform using healthy human plasma illustrating the principle of operation for analyzing plasma EV-miRNA. The representative CVCs are for three analyses: the miR-21 oligoprobe on the IEM sensor in only buffer solution (PBS buffer), the unlysed plasma sample (free-floating), and the SAW-lysed plasma sample (total). The relative voltage shifts reflect the concentration of free-floating miR-21(ΔV ≈ 0.1 V) and total (free-floating plus EV-contained) miR-21 (ΔV ≈ 0.7 V) in healthy human plasma, respectively
