Table 2 Candidate genes with high posterior probability of causality

From: Functional annotation and Bayesian fine-mapping reveals candidate genes for important agronomic traits in Holstein bulls

Gene

Traits

Gene PPC

Minimal p-values

ABCG2

Fat|Fat_Percent|Milk|Net_Merit|Pro_Percent|Protein

0.85~1.00

1.1E-09~1.5E-221

TMTC2

Final_score|Fore_udder_att|Front_teat_pla|

Rear_teat_pla|Rear_ud_height|Teat_length

0.95~1.00

1.2E-09~4.9E-26

ARRDC3

Dtr_Calv_Ease|Rear_ud_height|Sire_Calv_Ease

|Strength|Teat_length|Udder_depth

0.56~0.91

8.4E-09~2.7E-15

ABCC9

Dairy_form|Dtr_Preg_Rate|Fore_udder_att|Milk

|Protein|Udder_depth

0.999~1.00

4.4E-07~2.6E-21

DGAT1

Milk|Net_Merit|Pro_Percent|Protein|SCS

0.99~1.00

1.5E-21~2.0E-260

VPS13B

Fat_Percent|Milk|Pro_Percent|Rear_ud_height|Udder_cleft

0.97~1.00

1.5E-07~1.5E-76

ZNF613

Body_depth|Net_Merit|Sire_Still_Birth|Stature|Strength

0.61~0.84

2.2E-14~8.9E-37

CCND2

Body_depth|Rump_width|Stature|Strength

0.71~1.00

2.4E-19~4.5E-26

MGST1

Fat|Fat_Percent|Milk|Pro_Percent

0.999~1.00

7.1E-21~2.4E-75

FGF6

Body_depth|Rump_width|Stature|Strength

0.76~1.00

1.1E-07~3.9E-21

CCDC88C

DFB_PTA|Dairy_form|Rear_ud_height

0.89~1.00

2.7E-10~2.9E-22

LOC751788

Dairy_form|Final_score

0.92|0.96

4.2E-09|1.4E-11

SCD

Fat|Fat_Percent

1.00|1.00

9.7E-13|4.6E-10

MKL1

Milk|Protein

1.00|1.00

2.0E-14|2.9E-10

SYT8

Final_score|Foot_angle

1.00|0.998

1.6E-10|1.4E-09

LOC782261

Milk|Net_Merit

0.92|0.61

6.5E-09|3.8E-10

CHEK2

Dtr_Calv_Ease|Sire_Calv_Ease

0.65|0.67

1.9E-12|3.8E-07

C8H9orf3

Final_score|Rump_width

1.00|0.63

1.2E-09|3.5E-09

GC

Cow_Conc_Rate|Udder_depth

1.00|0.69

8.5E-08|1.8E-09

KALRN

Cow_Conc_Rate|Dtr_Preg_Rate

0.54|0.92

1.4E-07|2.8E-08

CSN1S1

Pro_Percent|Protein

0.999|1.00

1.2E-14|8.7E-14

SCAPER

Fore_udder_att|Front_teat_pla

0.999|0.77

5.3E-08|3.3E-08

TCP11

Stature|Udder_depth

1.00|0.97

5.9E-15|3.1E-08

PAEP

Fat_Percent|Protein

0.996|0.84

2.0E-11|1.1E-07

ANKFN1

Rump_width|SCS

0.98|0.87

1.5E-09|3.8E-07

NADSYN1

Dtr_Preg_Rate|Stature

0.65|0.99

2.9E-08|3.3E-07

LOC100852273

Final_score|Fore_udder_att

0.995|0.97

3.2E-09|8.4E-09

RAB6A

Milk|Pro_Percent

0.79|0.72

2.1E-13|3.5E-13

LOC107132925

Fore_udder_att|Udder_depth

0.75|0.999

1.6E-15|9.7E-18

POLD1

Foot_angle|Protein

0.98|0.99

3.8E-12|4.7E-13

RAB11FIP2

Front_teat_pla|Rear_teat_pla

0.83|0.64

2.5E-10|1.5E-07

MGMT

Rump_angle

1

4.15E-11

BOSTAUV1R417

Sire_Still_Birth

1

1.64E-16

SLC50A1

Pro_Percent

1

2.48E-11

RNF217

Pro_Percent

1

2.29E-09

LOC104974054

Rump_angle

1

3.19E-15

HSD17B12

Fat_Percent

1

9.24E-10

LOC104975270

Fore_udder_att

1

3.69E-11

LOC104972568

Sire_Calv_Ease

1

4.13E-10

ADGRV1

Sire_Calv_Ease

1

4.93E-10

CD276

Dtr_Preg_Rate

1

3.86E-11

TTC28

Dtr_Calv_Ease

1

4.98E-10

LSP1

Udder_depth

1

2.95E-12

VEPH1

Udder_cleft

0.999

3.49E-07

TIGAR

Prod_Life

0.999

9.64E-17

CCDC57

Fat

0.999

2.12E-09

GON4L

Protein

0.998

1.45E-10

FASN

Fat_Percent

0.998

7.47E-10

COLEC12

Rump_angle

0.997

1.05E-08

C6

SCS

0.997

3.95E-08

MYH10

Udder_depth

0.996

1.71E-09

GPAT4

Fat_Percent

0.995

3.93E-11

EXOC6B

Teat_length

0.992

1.09E-09

ABO

Pro_Percent

0.988

4.37E-11

LOC619012

Sire_Still_Birth

0.988

5.09E-09

MRGPRG

Sire_Calv_Ease

0.987

3.63E-07

FSTL1

Stature

0.985

2.13E-08

SFTPD

Pro_Percent

0.985

3.92E-10

SLC24A2

Rump_angle

0.973

5.17E-09

ESR1

Dtr_Calv_Ease

0.971

2.29E-11

LDLR

SCS

0.965

2.85E-08

TBC1D22A

Pro_Percent

0.947

3.73E-14

PTCH1

Body_depth

0.941

7.46E-09

LOC101903327

Prod_Life

0.936

9.30E-06

FAM98B

Stature

0.93

5.08E-08

VWA2

Teat_length

0.929

7.82E-06

LOC786966

Pro_Percent

0.919

1.33E-08

MROH9

Rear_teat_pla

0.908

1.27E-08

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