Fig. 7

Good correlation was observed between manually measured and algorithm-based TVD and FCD throughout initiation of cardiopulmonary bypass. TVD and FCD were compared by field of view before and after initiation of cardiopulmonary bypass (n = 39). Dashed lines represent identity lines. Good correlation was observed for TVD (r = 0.7, p < 0.0001, bias 0.0 mm mm−2, level of agreement −7.3 to 7.3 mm mm−2, precision 3.6 mm mm−2, percentage error 1.9%) and FCD (r = 0.7, p < 0.0001, bias −0.6 mm mm−2, level of agreement −7.6 to 6.5 mm mm−2, precision 3.5 mm mm−2, percentage error −0.5 %). Dashed lines represent identity lines. In Bland–Altman analysis, solid line represents bias and dotted lines represent ±2σ levels of agreement for all data. TVD total vessel density, FCD functional capillary density