Table 2 The identification of host ERAD (endoplasmic reticulum-associated protein degradation) and symbiont SELMA (symbiont-derived ERAD-like machinery) components in N. oceanica (NO), N. gaditana (NG), P. tricornutum (PT), C. merolae (CM), and G. sulphuraria (GS)
Species | NOa | NGa | PTa | CMa | GSa | ||||
|---|---|---|---|---|---|---|---|---|---|
H | S? | H | S? | H | S | ||||
ER translocation | Sec61 | X | − | X | − | X | − | X | X |
Derlin protein | Dfm1, hDer1-1 (sDer1-1) | X | Xsp | X | X | X | X | X | X |
Der1, hDer1-2 (sDer1-2) | X | − | X | − | X | X | X | X | |
Ubiquitinylation | Hrd1/Der3 (ptE3p) | X | − | X | − | X | X | X | X |
Hrd3 | − | − | − | − | X | − | X | X | |
Uba1 (sUba1) | X | X | X | X | X | X | X | X | |
Doa10 | X | − | X | − | X | − | X | X | |
Ubc6 (sUbc6) | Xsf | − | X | − | X | X | X | X | |
Polyubiquitin (sUbi) | X | − | X | − | X | X | − | − | |
Cdc48 complex | Cdc48 (sCdc48-1) | X | − | X | − | X | X | X | X |
(sCdc48-2) | − | − | − | − | − | X | − | − | |
Ufd1 (sUfd1) | X | − | X | − | X | X | X | X | |
Npl4 (sNpl4) | X | − | X | − | X | X | X | X | |
(sUBX) | − | − | − | − | − | X | X | X | |
(sPUB) | − | − | − | − | − | X | − | − | |
Processing | Png1 (sPng1) | X | X | X | X | X | X | X | X |
Dsk2 (sUbq) | X | X | − | X | X | X | X | X | |
Rad23 | X | − | X | − | X | − | X | X | |
Ufd2 | X | − | X | − | X | − | X | X | |
(ptDUP) | − | − | − | − | − | X | − | − | |
Unknown function | (PPP1) | X | − | X | − | − | X | X | X |
Chaperones | Hsp70 (sHsp70) | X | Xsp | X | X | X | X | X | X |
Hsp40/Ydj1/MAS5 | X | − | X | − | X | − | X | X | |
(sDPC) | − | − | − | − | − | X | − | − |
