Fig. 3
From: Congenital goitrous hypothyroidism is caused by dysfunction of the iodide transporter SLC26A7
Radio iodide transport and uptake assays. a Measured intracellular iodide after supplementation with radioactive NaI for 5 min. SLC26A7 or SLC26A4 was induced by doxycycline 24 h before the assay. Data represent the means ± SD. n = 3 biologically independent samples. *p < 0.05. b A schematic diagram of the iodide transport assay using the bicameral system. c, d Measured iodide in the top chamber (c) and inside the cell (d) after supplementation with radioactive NaI for 45 min. SLC26A7 or SLC26A4 was induced by doxycycline 24 h before the assay. Data indicate the means ± SD. n = 4 biologically independent samples. *P < 0.05
