Fig. 4 | Communications Biology

Fig. 4

From: Transient heat release during induced mitochondrial proton uncoupling

Fig. 4

Identification of transient heat shock from mitochondrial proton uncoupling. a Representative data for an intracellular response with BAM15 is plotted (red) along with the control experiments (extracellular responses in blue, and heat of mixing in black). b A statistically averaged intracellular response from n = 6 trials is shown with the mean and the SD, and plotted along with control experiments. BAM15 responses begin at t = 0 min (p < 0.001 between intracellular and extracellular responses). c Representative ΔT measurement (n = 6) following BAM15 exposure is fit to a biexponential function (red). The intracellular temperature signals are a mix of two exponential decays: one with a short time constant, τ1, and other with a long time constant, τ2. d Time constants τ1 and τ2 (*p < 0.05) extracted from the measured ΔT data shown in Fig. 4b. The data are represented on a logarithmic scale

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