Fig. 10 | Communications Biology

Fig. 10

From: Tpz1TPP1 prevents telomerase activation and protects telomeres by modulating the Stn1-Ten1 complex in fission yeast

Fig. 10

Summary and working model for telomere regulation. a A working model depicting how the SWSSS motif contributes to promote Stn1-Ten1-dependent telomere protection and prevent telomere extension by coordinating with Ccq1 Thr93 phosphorylation and Tpz1 Lys242 SUMOylation. b A summary of how TEL-patch and SWSSS motifs contribute to telomere length regulation by modulating telomerase recruitment, activation, and dissociation at telomeres

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