Fig. 1

Structures of investigated 3-benzazepines and ifenprodil. a–d. Structures of the highly active compounds ifenprodil (a), (R)-1 (b), (S)-1 (c) and 2 (d). Border color serves as an identifier for the compounds in Figs. 2, 4, 5, 7. e–j. Structures of 3-benzazepines rac-1 (e), 3 (f), 4 (g), 5 (h), 6 (i) and 7 (j) with more pronounced structural modifications. Border color serves as an identifier for the compounds in Fig. 4