Table 1 Sample characteristics (mean ± SD).
n = 60 | |
|---|---|
Sex | 42w/18 m |
Age | 59.6 ± 5.5 |
Education | 15.4 ± 3.2 |
Right-handed | 59 |
Ethnicity | Caucasian |
Dementia rating scale | 142.1 ± 2.3 |
Raven’s progressive matrices | 50.5 ± 4.9 |
Mill Hill vocabulary scale | 26.9 ± 3.9 |
Body mass index (kg/m²) | 24.6 ± 2.9 |
Anxiety | 2.6 ± 2.5 |
Mood | 4.4 ± 4.7 |
Caffeine (cups/day) | 3.6 ± 1.9 |
Alcohol (doses/week) | 3.9 ± 4.0 |
Treated for hypertension (stable > 6 months) | 7 |
Treated for hypothyroidism (stable > 6 months) | 12 |
Systolic blood pressure (mmHg) | 118.74 ± 11.62 |
Sleep quality | 5.1 ± 3.0 |
Daytime sleepiness | 6.2 ± 3.9 |
Chronotype | 53.8 ± 8.3 |
Clock time of dim-light melatonin onset (hh:min, PM) | 08:20 ± 00:59 |
In-lab baseline sleep duration (min, EEG) | 388.0 ± 44.3 |
In-lab baseline sleep efficiency, including N1 stage (%, EEG) | 82.6 ± 9.6 |
Baseline sleep time (hh:min, PM) | 10:47 ± 00:36 |
Baseline wake time (hh:min, AM) | 06:46 ± 00:43 |
Gray matter volume (% of total volume) | 41.04 ± 3.73 |
[18F]Flutemetamol (SUVR) | 1.16 ± 0.08 |
[18F]THK-5351 (SUVR) | 1.32 ± 0.10 |
