Fig. 6: Flow chart of the consensus protein pileups methodology: an iterative process in two parallel worlds. | Communications Biology

Fig. 6: Flow chart of the consensus protein pileups methodology: an iterative process in two parallel worlds.

From: Placental malaria vaccine candidate antigen VAR2CSA displays atypical domain architecture in some Plasmodium falciparum strains

Fig. 6

Bowtie2 aligned raw reads to a reference genome were translated to amino acids (AA) sequences as peptides reads, manually edited in the consensus protein pileups tool, and untranslated back to DNA reads for re-alignment in Bowtie2. This cyclic process continues until convergence.

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