Fig. 5: Compound-17 forms sub-optimal interactions when mapped onto site I. | Communications Biology

Fig. 5: Compound-17 forms sub-optimal interactions when mapped onto site I.

From: Glutathione facilitates enterovirus assembly by binding at a druggable pocket

Fig. 5

a GSH (cyan) superposed on compound-17 (purple) by matching surrounding protein structure8. The superpositions of a carboxylic acid group and a sulphur between the two are marked with ellipses. b Compound-17 (purple) bound to CVB3 (PDB: 6GZV)8. Protomer A VP1 is blue and VP3 magenta. Promoter B is in grey. c GSH positioned by superposition of the surrounding protein into CB-V3.

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