Fig. 3: Visualization of increased lacunar density in femoral cortices of STZ group. | Communications Biology

Fig. 3: Visualization of increased lacunar density in femoral cortices of STZ group.

From: Hyperglycemia compromises Rat Cortical Bone by Increasing Osteocyte Lacunar Density and Decreasing Vascular Canal Volume

Fig. 3

ad Representative scanning electron microscopy (SEM) and eh H&E-stained histology images, i quantification of osteocyte lacuna number in the SEM images in ad, j quantification of osteocyte lacuna number in the histology images in eh, k illustration of increased cellular density in the femur cortices of STZ group. In both SEM and histology images, femoral cortices of STZ group appeared more cellular than the euglycemic group (white arrows indicate osteocyte lacunae, two-way ANOVA and post-hoc Newman–Keuls for i, Student’s t-test for j, mean ± SD, *p < 0.05, **p < 0.01, ***p < 0.001, and ****p < 0.0001, n = 3 animals, scale bars represent 100 μm (ad, g, h) and 300 µm (e, f)).

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