Fig. 5: Gene ontology categorizes under selection in C. hominivorax.

a Distribution of the dN/dS ratios across GO terms. GO terms represented by at least 30 genes were used. Some categories have accelerated rates of evolution compared to the other genes of the genome (median dN/dS of the genes in the category is higher than the median of the other genes in the genome). Other categories are more constrained than the genomic average. The center lines in the boxes indicate the median of each distribution. Lower and upper hinges correspond to the first and third quartiles, and the whiskers extend to the largest or smallest value, no further than 1.5x the inter-quartile range. Outliers are not shown. The dashed vertical line shows the genome-wide median. The asterisks show the terms with dN/dS distributions statistically different from the genome-wide distribution (Mann–Whitney U test). b Developmental RNA-seq of genes belonging to two gene ontology categories with median dN/dS higher than the genome, based on Supplementary Data 8. Each expression value represents the average of three biological replicates for each stage.