Fig. 2: Bedaquiline binds in the a/c interface.
From: Bedaquiline inhibits the yeast and human mitochondrial ATP synthases
a Side (left) and cytosolic (right) views of the cryo-EM maps of Fo with bound BDQ (purple) with the c-ring (gold) and subunit-a (red) contoured at 4.5σ. b Zoomed views of (a) with two perpendicular perspectives: a side view and a view from the intermembrane space in the core of the c10-ring.
