Fig. 2: Relationships among predicted nematode BCL-2 proteins and alignment of the region between the BH3 on helix α4 and the BH1 domain on helix α5.
From: Diversity in the intrinsic apoptosis pathway of nematodes
Consensus Bayesian phylogenetic tree of predicted nematode BCL2 proteins. Tree tips are labelled by species name and sequence identity number (see Supplementary Table 2). a Branches are coloured by the posterior probability support values of adjacent nodes, where black is 0.5 and red is 1.0. b Colours of each amino acid residue in the selected region of the Bcl-2 sequence alignment. Tree scale represents 0.3 substitutions per site. *Trichuris suis sequence derived from resolved crystal structure (see Fig. 1) #Caenorhabditis elegans sequence derived from the published three-dimensional structure (PDB ID# 1OHU chain A) with an artificially larger gap between helices α4 and α5 due to there not being any electron density for that part of the structure.
