Fig. 6: Data from mice immunized with all three HK-B.

a Characterization of HK-B-binding IgGs in mice immunized with a mixture of HK-ST, HK-EB, and HK-PA. b Average heat-maps found in HK-EB, -ST, and -PA immunized mice, and in individually-immunized mice. Columns to the right and below show the sum of frequency in that category. c Difference between frequencies in the various categories found in HK-EB, -ST, and -PA immunized mice and in individually-immunized mice. *p-value < 0.05. Data for all panels is binned as described in the methods; and shown as a relative frequency of IgG in bin over total IgG for all mice in the respective category.