Table 1 Characteristics of 1995 patients enrolled in this study.

From: Genetic and clinical landscape of breast cancers with germline BRCA1/2 variants

 

Number of patients

Age

   ~35

51

   36–45

317

   46–55

461

   56–65

522

   66

644

Histology

   IDC

1484

   ILC

74

   DCIS

212

   Others

106

Phenotype

   ER+

1540

   ER−

377

   HER2+

310

   HER2−

1382

   Ki67 high (>14)

967

   Ki67 low

721

Histological grade

   3

146

   2

419

   1

217

Clinical stage

   0

254

   I

774

   II

733

   III

142

   IV

53

   Unknown

39

Past history

   Ovarian cancer

14

Family historya

 

   Breast cancer

348

   Ovarian cancer

33

  1. Abbreviations: IDC Invasive ductal carcinoma, ILC invasive lobular carcinoma, DCIS ductal carcinoma in situ.
  2. aFamily history refers to reported breast or ovarian cancer in first or second-degree relative.
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