Table 1 Identified protein antigens and knowledge-based investigation of their interactions with autoimmune diseases.

From: Focal adhesion ribonucleoprotein complex proteins are major humoral cancer antigens and targets in autoimmune diseases

Antigens

Full name

Identified as an autoantigen in autoimmune diseases

Reference

FLNA

Filamin A

Rheumatoid arthritis

Pianta et al.11

Myasthenia gravis

Yamamoto et al.12

DLAT

Dihydrolipoamide S-acetyltransferase

Primary biliary cirrhosis

Van de Water et al.13

PABPC1

Poly-A binding protein cytoplasmic 1

Myasthenia gravis

Becker et al.14

GRB7

Growth factor receptor bound protein 7

Rheumatoid arthritis

Choong et al.15

LMNA

Lamin A

Primary biliary cirrhosis

Hu et al.16

Rheumatoid arthritis

Lassoued et al.17

Sjogren’s syndrome

Zhang et al.18

HSP90a

Heat shock protein 90

Systemic lupus erythematosus

Minota et al.19

Rheumatoid arthritis

Mantej et al.20

Multiple sclerosis

Cid et al.21

EZRa

Ezrin

Rheumatoid arthritis

Wagatsuma et al.22

EML3

EMAP like 3

Not identified yet

 
  1. aEzrin and HSP90 were identified in our previous study (Katoh et al.9).