Fig. 1: A hierarchical clustering of the 21 core genera based on association with nutrition intake.

Columns correspond to the 21 core genera in the Japanese gut; rows correspond to nutrition intake measured by BDHQ. Red and blue denote positive and negative associations, respectively. The intensity of the colors represents the degree of association between the genus abundance and nutrition intake as measured by multiple linear regression analysis. Bacterial phyla are summarized by the color code on the top right. The dots indicate the associations that are significant after adjusting for multiple testing of 138 variables. Columns and rows are subjected to hierarchical clustering. The genera in cluster I are indicated in red, and those in cluster II are indicated in green. All regression coefficient values are listed in Supplementary Data 5.