Fig. 2: Significant associations of the genetic loci for the gut microbiota. | Communications Biology

Fig. 2: Significant associations of the genetic loci for the gut microbiota.

From: Genome-wide association studies and heritability analysis reveal the involvement of host genetics in the Japanese gut microbiota

Fig. 2

a, c, e, g, i Manhattan plots of (a) Prevotella in males, (c) Faecalibacterium in males, (e) Oscillospira in females, (g) Erysipelotrichaceae;g in females, and (i) the diversity index Chao1 in females under the additive model for (a, c, g) and the dominant model for (e, i). b, d, f, h, j Box plots of (b) Prevotella in males, (d) Faecalibacterium in males, (f) Oscillospira in females, (h) Erysipelotrichaceae;g in females, and (j) the diversity index Chao1 in females. The red line represents a genome-wide significance level (P = 8.9 × 10−8), and the blue line represents a genome-wide suggestive level (P = 1 × 10−5). In each box plot, the x-axis indicates the minor allele count of the SNP indicated on the top, and the y-axis represents the Box–Cox–transformed relative abundances of the genera (b, d, f, h) and the alpha diversity index Chao1 (j). Descriptive statistics are listed in Supplementary Data 8.

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