Table 1 MICs of T405, imipenem and faropenem tested against the reference strain (ATCC 19977) and 20 clinical strains of M. abscessus in vitro.

From: Development of a penem antibiotic against Mycobacteroides abscessus

Isolate #

T405

Imipenem

Faropenem

MIC (μg/ml)

ATCC 19977

2

8

512

1N

2

8

256

2N

2

8

256

3N

2

8

256

4N

1

16

256

5N

1

16

512

11N

8

32

512

13N

1

8

64

14N

8

32

512

202

2

16

512

203

2

32

128

204

8

32

512

214

1

8

128

215

2

16

512

JHH2

4

32

512

JHH4

2

16

512

JHH9

4

16

512

8N

4

32

512

JHHKB

2

256

512

JH1801

1

16

512

JH1802

4

16

256

  1. MIC50 and MIC90 of imipenem are 16 and 32 µg/mL and for faropenem are 512 and 512 µg/mL, respectively.
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