Fig. 3: Application of the sRIN assay on well-preserved clinical samples.
From: The spatial RNA integrity number assay for in situ evaluation of transcriptome quality
a–l Luminal B breast tumor tissue sections from two patients (n = 3, technical replicates each). a HE image (scale bar: 1 mm) and b sRIN heat map, boxes enclose regions shown in close-up. Close-up of c HE image (scale bar: 200 µm) and d sRIN heat map. e HE image (scale bar: 1 mm) and f sRIN heat map, boxes enclose regions shown in close-up. Close-up of g HE image (scale bar: 150 µm) and h sRIN heat map. Close-up of i HE image (scale bar: 200 µm) and j sRIN heat map. Close-up of k HE image (scale bar: 100 µm) and l sRIN heat map, arrows show areas of very high (10) sRIN values and varied cell density. m HE image (scale bar: 80 µm) and n sRIN heat map of a gray matter region from a post-mortem brain (n = 3, biological replicates).
