Fig. 4: Comparison of European and Malagasy populations, based on common genetic variants.

A Venn diagram demonstrating the level of overlap of shared single-nucleotide variants (SNVs) between the European and Malagasy populations. B Principal component analysis (PCA) of representative specimens from ten European and five Malagasy populations. C Heatmap of SNV patterns, based on the 8912 common polymorphic sites. The color represents the average number of SNVs per site, as indicated. The clustering reflects the specific geographical SNV patterns.