Fig. 1: Effect of radiation therapy on local tumor, and survival.

a Experimental procedure of TC-1 tumor model and treatments. b, c Flow cytometry analyses (n = 4 mice per group). Dynamic changes of CD8 + T cells (b) and the ratio of CD8 + T cells to Tregs (c) in tumors. d Tumor growth curves of mice bearing TC-1 tumors with or without RT treatments (n = 10 mice per group). e Experimental procedure of 4T1-Luc2 tumor model and treatments. f Tumor growth curves of mice bearing 4T1-Luc2 tumors with or without radiation treatment. g Survival of mice bearing 4T1-Luc2 tumors treated with or without radiation (n = 10 mice per group). Results are expressed as mean ± SD. Experiments were repeated two times and two-tailed t-test was used for comparisons of biological replicates. ^*P < 0.05, ^**P < 0.01, ^***P < 0.001.