Table 2 Correlation scores between clinical and task parameters.

From: A cross-species assessment of behavioral flexibility in compulsive disorders

OCD patients

 

Trials to reversal

Reversal errors

Trials in acquisition phase

BF10 = 0.28, r = 0.14 [−0.18 0.42]

 

Fluoxetine-equivalent dose

BF10 = 0.24, r = −0.105 [−0.39 0.21]

BF10 = 0.31, r = 0.16 [−0.16 0.43]

YBOCS

BF10 = 0.2, r = 0.03 [−0.28 0.33]

BF10 = 0.2, r = 0.02 [−0.29 0.32]

BDI

BF10 = 0.34, r = −0.17 [−0.44 0.15]

BF10 = 0.21, r = 0.05 [−0.25 0.35]

STAI-A

BF10 = 0.22, r = 0.08 [−0.23 0.37]

BF10 = 0.21, r = 0.03 [−0.25 0.35]

STAI-B

BF10 = 0.22, r = −0.08 [−0.37 0.23]

BF10 = 0.2, r = 0 [−0.3 0.3]

OCI-R total score

BF10 = 0.2, r = −0.02 [−0.31 0.29]

BF10 = 0.33, r = 0.17 [−0.15 0.44]

OCI-R checking subscore

BF10 = 2.96, r = 0.37 [0.06 0.6]

BF10 = 0.2, r = 0 [−0.3 0.3]

OCI-R washing subscore

BF10 = 0.47, r = −0.22 [−0.48 0.1]

BF10 = 0.23, r = 0.1 [−0.21 0.38]

OCI-R order subscore

BF10 = 0.27, r = −0.13 [−0.41 0.18]

BF10 = 0.2, r = 0.04 [−0.27 0.33]

OCI-R hoarding subscore

BF10 = 0.2, r = 0.04 [−0.27 0.33]

BF10 = 0.24, r = -0.11 [−0.39 0.2]

OCI-R obsession subscore

BF10 = 0.2, r = 0.02 [−0.29 0.32]

BF10 = 0.53, r = 0.23 [−0.09 0.49]

OCI-R neutralization subscore

BF10 = 0.25, r = −0.12 [−0.4 0.2]

BF10 = 0.42, r = 0.2 [−0.11 0.47]

 

OCI-R checking

SSC probability as %

BF10 = 4.54, r = 0.4 [0.1 0.62]

SSC errors

BF10 = 0.58, r = 0.24 [−0.08 0.5]

SCAPE probability as %

BF10 = 0.38, r = -0.19 [−0.46 0.13]

SCAPE errors

BF10 = 0.42, r = 0.2 [−0.11 0.47]

Sapap3 KO mice

 

Trials to reversal

Reversal errors as %

Number of grooming bouts

BF10 = 0.32, r = 0.16 [−0.23 0.49]

BF10 = 0.65, r = −0.29 [−0.59 0.11]

Time spent grooming as %

BF10 = 0.29, r = −0.12 [−0.46 0.27]

BF10 = 0.49, r = −0.25 [−0.55 0.15]

  1. In patients, only the checking dimension influences the performance in our task; whereas in Sapap3 KO mice, there is no influence of grooming severity. A BF10 greater than one is in favor of a correlation and vice versa. The further the BF10 is from one, the greater the evidence. A BF10 greater than 3 (or lower than 1/3) is commonly considered a significant evidence. OCI-R obsessive compulsive inventory revised, YBOCS Yale-Brown obsessive-compulsive scale, BDI Beck depression inventory, STAI Spielberger’s state (A)–trait (B) anxiety inventory, BIS-10 Barratt impulsivity scale, fNART French national adult reading test, SSC spontaneous strategy change, SCAPE strategy change after a probabilistic error.
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